Asymmetric bilateral optic neuritis as the first presenting feature secondary to undiagnosed vitamin-B12 deficiency

Vitamin B12 deficiency presenting as pyrexia.

Vitamin B12 deficiency is an uncommon cause of pyrexia. We report the case of a patient who presented with pyrexia and anaemia, which after exclusion of infective, inflammatory or endocrine causes was attributed to megaloblastic anaemia secondary to vitamin B12 deficiency. The patient's fever responded to treatment of vitamin B12 deficiency.

Multiple sclerosis in childhood: presenting as bilateral optic neuritis.

Multiple sclerosis is a disease of adolescence and middle age. Though rare, it is being increasingly recognized in younger population. We describe two patients in whom multiple sclerosis was diagnosed before 10 years of age. Both patients had bilateral optic neuritis during the course of their illness with partial recovery; other lesions in the neuraxis recovered reasonably well.

Glossitis secondary to vitamin B12 deficiency anemia.

Lhermitte's sign as the presenting symptom of vitamin B12 deficiency.

A 47-year-old garage proprietor presented with a three-month history of numbness and tingling of his feet and subsequently of both hands. These symptoms were accompanied by a sensation of electric shocks in his arms and legs, precipitated by forward flexion of the neck. There was no history of trauma to the cervical spine and he had previously been in good health. General physical examination w...

CASE REPORT Vitamin B12 deficiency presenting as acute ataxia

To cite: Crawford JR, Say D. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-008840 SUMMARY A previously healthy 7-year-old Caucasian boy was hospitalised for evaluation of acute ataxia and failure to thrive, initially suspicious for an intracranial mass. Weight and body mass index were below the third percentile and he demonstrated loss of joint position an...